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1 / 1
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DeCS
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Descriptor English:
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Patched-1 Receptor
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Descriptor Spanish:
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Receptor Patched-1
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Descriptor Portuguese:
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Receptor Patched-1
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Synonyms English:
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PTCH1 Protein
Patched 1 Protein
Patched 1 Receptor
Patched Homolog 1
Patched Homolog-1
Patched Receptor 1
Patched Receptor-1
Patched-1 Protein
Receptor, Patched-1
Receptor-1, Patched
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Tree Number:
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D12.776.543.750.058.500
D12.776.624.776.633.500
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Definition English:
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A patched receptor for several HEDGEHOG PROTEINS that associates with the SMOOTHENED RECEPTOR to modulate hedgehog signaling. It is also a TUMOR SUPPRESSOR PROTEIN; mutations in the patched-1 gene are associated with BASAL CELL NEVUS SYNDROME; SQUAMOUS CELL CARCNIOMA of the ESOPHAGUS; trichoepitheliomas, and CARCINOMA, TRANSITIONAL CELL of the URINARY BLADDER. |
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History Note English:
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2017 (1996)
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Allowable Qualifiers English:
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Record Number:
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56641
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Unique Identifier:
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D000072081
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Occurrence in VHL:
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Similar:
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DeCS
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